Endocrine Abstracts

A 69 year old man presented to hospital with acute hypercalcaemia and renal failure. History included nephrectomy for a benign renal tumour and thyroidectomy for thyroid carcinoma. Presentation adjusted calcium was 2.70 mmol/L with an incompletely suppressed parathyroid hormone level of 0.6 pmol/L. The hypercalcaemia was resistant to both intravenous fluids and bisphosphonates, rising to 3.20 mmol/L. Given his previous cancer, hypercalcaemia of malignanc...

A 73-year-old lady presented with symptoms of weight-loss, tiredness, sweating and thyroid gland enlargement. Biochemistry demonstrated a T4 of 65.7 pmol/L and TSH <0.02 mmol/l. TSH receptor antibodies were positive confirming Graves’ disease. Thyroid ultrasound demonstrated reduced echogenicity and increased vascularity with a 3.2 cm left lobe U3 nodule and FNA planned.The patient developed a severe reaction within 17 days of star...

A 69 year old man presented to hospital with acute hypercalcaemia and renal failure. History included nephrectomy for a benign renal tumour and thyroidectomy for thyroid carcinoma. Presentation adjusted calcium was 2.70 mmol/L with an incompletely suppressed parathyroid hormone level of 0.6 pmol/L. The hypercalcaemia was resistant to both intravenous fluids and bisphosphonates, rising to 3.20 mmol/L. Given his previous cancer, hypercalcaemia of malignanc...

A 73-year-old lady presented with symptoms of weight-loss, tiredness, sweating and thyroid gland enlargement. Biochemistry demonstrated a T4 of 65.7 pmol/L and TSH <0.02 mmol/l. TSH receptor antibodies were positive confirming Graves’ disease. Thyroid ultrasound demonstrated reduced echogenicity and increased vascularity with a 3.2 cm left lobe U3 nodule and FNA planned.The patient developed a severe reaction within 17 days of star...

Case history: We present the case of a 64 year old gentleman diagnosed with hypoparathyroidism following presentation with acute hypocalcemia post thoracic aneurysm surgery for aortic dissection. The etiology was felt to be a complication of thoracic surgery with possible disruption of blood supply to the parathyroid glands.Deeper investigation at a subsequent review revealed persistent hypocalcaemia predating surgery by over 10 years. This was on the ba...